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. Author manuscript; available in PMC: 2017 Jun 6.
Published in final edited form as: J Cardiovasc Pharmacol. 2015 Oct;66(4):347–353. doi: 10.1097/FJC.0000000000000286

FIGURE 3.

FIGURE 3

Effect of omecamtiv mecarbil on pCa-ATPase activity relations of (A) TM54 and NTG myofibrils treated with both DMSO (vehicle) and 316 nM omecamtiv mecarbil over varying pCa values. ATPase values are given as mean ± SEM (n = 8– 14 hearts). B, Comparison of ATPase activity in NTG-Omecamtiv versus NTG-Vehicle myofibrils at pCa 6.6. C, Comparison of ATPase activity in NTG-Omecamtiv versus NTG-Vehicle myofibrils at pCa 7.4. Histograms present rates as mean ± SEM. *P < 0.05, **P < 0.01.