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. 2017 Jun 5;18:63. doi: 10.1186/s12881-017-0424-5

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — A1-4: The MRI of proband. A1-2 MRI revealed the bilateral thigh muscle disappear, the normal form was filled with a wide range of adipose tissue; A3-4 MRI showed the anteromedial calf group of muscles was infiltrated mild fatty. B1-2: Physical performance of proband; B1 (HE, ×100): the pathological changes in muscles showed that the sizes of muscle fibers were different, fiber atrophy (black arrow) and hypertrophy (blue arrow) alternately existed, compensatory hypertrophy of partial muscle fibers existed, fat and connective tissue proliferations were apparent. B2 (MGT, ×200): split muscle fibers can be seen in the hypertrophy muscle fibers (black arrow)