Fig 7 Final parsimonious structural equation model illustrating relations among alcohol consumption (average across study phases, as fraction of 100 units weekly), hippocampal volume (average, %intracranial volume), corpus callosum mean diffusivity (as multiplicative of 1000), decline in lexical fluency (slopes), and age in 511 participants. Values on arrows represent unit changes in dependent variable for 1 unit increase in predictor. Model explained 21% of corpus callosum mean diffusivity, 14% of hippocampal variance, and 2% of lexical fluency decline variance (R²). Model fit: χ²=5.6, df=4, P=0.23, root mean square error of approximation=0.03, comparative fit index=0.99, Tucker-Lewis index=0.97