Table 3.

Multivariate analysis of the first CMF study in 337 patients with known oestrogen receptor status. Final model

	Hazard ratio*	95% CI	P value (Wald test)
Relapse-free survival:
CMF v surgery alone	0.66	0.51 to 0.85	0.002
>3 affected lymph nodes v 1-3 affected lymph nodes	1.67	1.28 to 2.18	0.0001
Overall survival:
CMF v surgery alone	0.78	0.61 to 0.98	0.04
>3 affected lymph nodes v 1-3 affected lymph nodes	1.40	1.09 to 1.80	0.009
Age ≥50 v <50 years	1.43	1.12 to 1.82	0.004

^*A ratio of <1.0 favours CMF.