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. Author manuscript; available in PMC: 2018 Apr 18.
Published in final edited form as: Chem Soc Rev. 2017 Apr 18;46(8):2158–2198. doi: 10.1039/c6cs00765a

Fig 25.

Fig 25

Comparison of dynamic imaging capabilities of the various functional modalities used in small animal research and the clinics. Shown are: optical methods (violet) based on two photon microscopy (2P) [342], light-sheet microscopy (LSM) [343] and light field microscopy (LFM) [344]; small animal [345] and human [346] functional magnetic resonance imaging (fMRI - orange); high-density diffuse optical tomography (HD-DOT - gray) [347]; functional ultrasound (fUS - green) [348]; optical-resolution photoacoustic microscopy (OR-PAM) [22]; 4D and 5D optoacoustic tomography (4D-5D OAT) [255] (dots indicate three reported systems with isotropic resolution).