Table 3.
Relationship between indicated exposure at index visit and subsequent decline of >50% in GFR or initiation of RRT, n=751
| Exposure | No. | No. (%) with Event | Regression Modela | Relative Time | 95% Confidence Interval |
|---|---|---|---|---|---|
| Urine protein-to-creatinine, mg/mg | |||||
| <0.2 | 287 | 25 (9) | GG (3.553,1.086,0.690) | 1 (reference) | |
| 0.2–2.0 | 363 | 112 (31) | GG (2.393,1.086,0.690) | 0.31 | 0.21 to 0.47 |
| >2.0 | 101 | 65 (64) | GG (0.974,1.086,0.690) | 0.08 | 0.04 to 0.13 |
| Urine albumin-to-creatinineb, mg/g | |||||
| <56 | 287 | 31 (11) | GG (3.391,1.024,0.784) | 1 (reference) | |
| 56–1333 | 363 | 104 (29) | GG (2.428,1.024,0.784) | 0.38 | 0.26 to 0.55 |
| >1333 | 101 | 67 (66) | GG (1.031,1.024,0.784) | 0.09 | 0.06 to 0.15 |
| Urine nonalbumin-to-creatinineb, mg/g | |||||
| <118 | 287 | 25 (9) | GG (3.593,1.233,0.507) | 1 (reference) | |
| 118–715 | 363 | 112 (31) | GG (2.411,1.233,0.507) | 0.31 | 0.20 to 0.46 |
| >715 | 101 | 65 (64) | GG (0.936,1.233,0.507) | 0.07 | 0.04 to 0.12 |
GG, generalized gamma.
a
Includes the location, scale, and shape parameters of the regression model.
b
Cutoffs for urine albumin-to-creatinine and urine nonalbumin-to-creatinine were chosen to yield same sample sizes as determined by urine protein-to-creatinine cutoffs of 0.2 and 2.0.