Table 4.
Relationship between indicated exposure at index visit and subsequent decline of >50% in GFR or initiation of RRT, n=751
| Exposure | No. | No. (%) with Event | Regression Modela | Relative Time | 95% Confidence Interval |
|---|---|---|---|---|---|
| Urine protein-to-creatinineb, mg/mg | |||||
| <0.139 | 220 | 17 (8) | GG (3.721,0.935,0.991) | 1 (reference) | |
| 0.139–0.630 | 271 | 46 (17) | GG (3.043,0.935,0.991) | 0.51 | 0.30 to 0.86 |
| >0.630 | 260 | 139 (53) | GG (1.662,0.935,0.991) | 0.13 | 0.07 to 0.22 |
| Urine albumin-to-creatinine, mg/g | |||||
| <30 | 220 | 23 (10) | GG (3.469,0.932,0.977) | 1 (reference) | |
| 30–300 | 271 | 46 (17) | GG (3.001,0.932,0.977) | 0.63 | 0.40 to 1.00 |
| >300 | 260 | 133 (51) | GG (1.663,0.932,0.977) | 0.16 | 0.10 to 0.26 |
| Urine nonalbumin-to-creatinineb, mg/g | |||||
| <86 | 220 | 18 (8) | GG (3.913,0.336,3.328) | 1 (reference) | |
| 86–273 | 271 | 49 (18) | GG (3.166,0.336,3.328) | 0.47 | 0.27 to 0.84 |
| >273 | 260 | 135 (52) | GG (2.065,0.336,3.328) | 0.16 | 0.09 to 0.28 |
GG, generalized gamma.
a
Includes the location, scale, and shape parameters of the regression model.
b
Cutoffs for urine protein-to-creatinine and urine nonalbumin-to-creatinine were chosen to yield same sample sizes as determined by urine albumin-to-creatinine cutoffs of 30 and 300.