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PERP is downregulated in SG compared with DG tumors and normal pituitary. (a) Perp transcript levels are significantly repressed in SG tumors compared with DG or normal pituitary samples. *P < 0.001. (b) Downregulation of PERP was confirmed at the mRNA level by qPCR. *P < 0.001. (c) Low PERP protein levels in SG tumors are also seen by immunoblot. (d) Perp is low in GH3 rat pituitary cell model compared with rat liver control by qPCR.
