Figure 2.

Preterm baboons are born at 67% completed gestation, compared with term controls at two to three weeks of age after insulin stimulation. (a) Hepatic IR-β protein content, (b) IR mRNA, (c) protein content of phosphorylated Tyr 612 of IRS-1 normalized to IRS-1, (d) Akt-1 gene expression, and (e) protein content of the p85 subunit of PI3K were measured by Western blot or quantitative reverse transcription-PCR (n = 5 to 6 per group, *P < 0.05). Representative blots from each group are shown. All data shown as mean ± standard error of the mean. au, arbitrary units.