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. 2017 Jan 23;158(5):1130–1139. doi: 10.1210/en.2016-1451

Figure 1.

Figure 1.

Acute effects of a single PTH injection in WT mice. Baseline cFGF23 levels in different experiments ranged between 218 ± 19 and 345 ± 34 pg/mL, and peak cFGF23 levels ranged between 578 ± 114 and 1244 ± 110 pg/mL; therefore, changes in cFGF23 (and iFGF23) levels are reported as percentage of change from baseline. (a) Plasma phosphate levels 2, 6, and 24 hours after PTH or vehicle injection. (b) Plasma cFGF23 levels, expressed as percentage over preinjection baseline, at 2, 4, 6, and 24 hours after PTH injection. (c) Plasma iFGF23 levels, expressed as percentage over preinjection baseline, at 2, 4, 6, and 24 hours after PTH injection. n = 5 or more mice per group. (d) Ratio of cleaved/total FGF23 was calculated as follows: (value measured by cFGF23 ELISA − value measured by iFGF23 ELISA)/value measured by cFGF23 ELISA. n = 7–8 per group. *P < 0.05.