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. 2017 May 24;11(5):e0005602. doi: 10.1371/journal.pntd.0005602

Table 4. The table shows simulated outcomes for 1000 P. vivax malaria patients of undetermined G6PD status at attendance, if they were managed according to each of three strategies (chloroquine, primaquine and screening) according to G6PD status, treatment given and the test result if screened.

Initial treatment by G6PD status Males Females
Strategy Strategy
Chloroquine Primaquine Screening Chloroquine Primaquine Screening
G6PD normal who get primaquine and have no recurrences 725 718 592 592
G6PD normal who get primaquine and have at least one recurrence 138 137 113 113
G6PD normal who get chloroquine only and have no recurrences 231 2 212
G6PD normal who get chloroquine only and have at least one recurrence 632 6 580
G6PD deficients* who get chloroquine only 137 208
G6PD deficients* who get weekly primaquine 136 106
Severe G6PD deficients who get 14 day primaquine, do not complete treatment but do not require a transfusion 122 1 40 0.40
Intermediate G6PD deficients who get 14 day primaquine and complete treatment 140 78
G6PD deficients* who get primaquine, hemolyze and receive a required transfusion 13 0.13 5 0.40
G6PD deficients* who get primaquine, hemolyze, do not receive a required transfusion and live 1 0.01 0.50 0.04
G6PD deficients* who get primaquine, hemolyze and die due to not receiving a transfusion 0.15 0.001 0.06 0.004
Do not receive primaquine due to pregnancy 110 110

* For women, this includes both severe and intermediate G6PD deficiency.