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. 2017 Jun 6;12(6):e0179009. doi: 10.1371/journal.pone.0179009

Table 2. Influences of repeated terminations and past treatment time on HRQoL: Linear regression analysis (N = 1212).

Independent variables SF-36v2PCS SF-36v2MCS QOL-DAv2.0
B (95%CI) P B (95%CI) P B (95%CI) P
Univariate analysis
Repeated terminations
    Yes 0.00 0.00 0.00
    No 1.33 (0.41, 2.25) 0.005 0.35 (-0.90, 1.60) 0.58 1.86 (-0.17, 3.89) 0.07
Past treatment time (year)a <0.001 0.31 0.032
    < 1 0.00 0.00 0.00
    1~ -1.09 (-2.66, 0.48) 0.17 -1.23 (-3.37, 0.91) 0.26 -1.17 (-4.64, 2.31) 0.51
    2~ -1.74 (-3.45, -0.04) 0.045 0.11 (-2.23, 2.43) 0.93 -0.16 (-3.95, 3.62) 0.93
    3~ -2.26 (-3.90, -0.62) 0.007 -0.89 (-3.13, 1.35) 0.44 -3.15 (-6.78, 0.48) 0.09
    ≥ 4 -3.15 (-4.53, -1.78) <0.001 -1.61 (-3.48, 0.27) 0.09 -3.87 (-6.91, -0.83) 0.013
Multivariate analysis Ɨ
Repeated terminations
    Yes 0.00 0.00 0.00
    No 0.76 (-0.18, 1.69) 0.11 0.09 (-1.19, 1.37) 0.89 1.17 (-0.89, 3.22) 0.27
Past treatment time (year)b 0.004 0.63 0.30
    < 1 0.00 0.00 0.00
    1~ -0.76 (-2.33, 0.81) 0.34 -1.07 (-3.23, 1.09) 0.33 -0.76 (-4.22, 2.71) 0.67
    2~ -1.64 (-3.36, 0.09) 0.06 0.20 (-2.17, 2.56) 0.87 -0.17 (-3.97, 3.64) 0.93
    3~ -1.72 (-3.38, -0.05) 0.043 -0.52 (-2.81, 1.77) 0.65 -2.28 (-5.95, 1.40) 0.23
    ≥ 4 -2.39 (-3.80, -0.97) 0.001 -1.05 (-2.99, 0.90) 0.29 -2.46 (-5.59, 0.66) 0.12

Ɨ Multivariate analysis was done after controlling following variables: age at initial treatment (year: ref. ≤ 30); gender (ref. male); education level (ref. primary and below); marital status (ref. married); employment status (ref. unemployed); age at initial drug use (year: ref. ≤ 20); detoxification before initial MMT (ref. yes); drug using methods over the past 6 months (ref. oral); syringe sharing experiences (ref. yes); and initial morphine urine test (ref. positive).

HRQoL: health-related quality of life. SF-36v2: short-form 36 health survey version 2. PCS: physical component summary. MCS: mental component summary. QOL-DAv2.0: quality of life scale for drug addicts. B: regression coefficient. 95%CI: 95% confidence interval.

a P-value is for the test of effect of past treatment time on HRQoL in univariate analysis.

b P-value is for the test of effect of past treatment time on HRQoL in multivariate analysis.