Skip to main content
. 2017 Mar 20;158(6):1859–1874. doi: 10.1210/en.2016-1707

Figure 9.

Figure 9.

miR-21 downregulation attenuated ALDO/SALT-mediated LV cardiac injury marker mRNA expression. Rats were treated with ALDO/SALT (A/S) or vehicle for 2 weeks. miR-21 antagomir (Antag) was administered starting on day 5 for 3 consecutive days. (a) LV mRNA levels of natriuretic peptide precursor A (Nppa) and (b) natriuretic peptide precursor B (Nppb) were quantified by RT-qPCR. Results are expressed as mean ± standard error of the mean (n = 5). *P < 0.05 versus control (Ctrl); #P < 0.05 versus A/S. AU, arbitary unit; GAPDH, glyceraldehyde 3-phosphate dehydrogenase.