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. 2017 Mar 22;158(6):1929–1938. doi: 10.1210/en.2017-00061

Figure 2.

Figure 2.

Deletion of both Vdr and Casr downregulates Vdr signaling in neonatal epidermis. (a, b) Gene expression profiling of neonatal (days P1 to P3) epidermis lacking both Vdr and Casr (DKO). (a) The heat maps for DKO show the fold changes (KO/CON) for representative genes for vitamin D signaling. (b) The changes in vitamin D3 target genes in DKO epidermis are shown with their subcellular localization and function. The lighter elements denote downregulation, and the darker elements denote upregulation.