Table 1. Conformational states of prokaryotic channel crystal structures.
Parameter | NavMs | NavAb | NavAb | NavRh | NavMs (pore) | NavAe1 (pore) | CavAb |
---|---|---|---|---|---|---|---|
Apparent state | open/ activated | closed/ preactivated | closed/ inactivated | closed/ inactivated | open/- | closed/- | closed/ preactivated |
VS | activated | preactivated | preactivated | preactivated | none | none | preactivated |
Pore gate | open | closed | closed | closed | open | closed | closed |
SF | open - Na ions | open - no ions | collapsed | collapsed | open - Na ions | open - no Na | open - Ca ions |
CTD | visible - interaction | not visible | not visible | not visible | not visible | visible - coiled-coil | visible - coiled-coil |
Conducts Na+ | yes | yes | yes | no | yes | no | NA |