Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Jun 5;216(6):1849–1864. doi: 10.1083/jcb.201612030

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2017 Schietroma et al.

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/).

PMC Copyright notice

Figure 7. — Pcdh15 knockdown in X. tropicalis causes distinct morphological alterations to the rod and cone outer segments and the associated calyceal processes (TEM analyses). (A) In longitudinal (left) and transverse (right) thin sections, control rod photoreceptors have the expected shape, with cylindrical, multilobed outer segments (OS). The calyceal processes (CPs) can be seen all around the OS, lying within (black arrowheads) and occasionally between incisures demarcating the lobes of the rod disks (see diagram). The base of the OS is congruent with the tip of the inner segment (IS; left, arrow). (B) In morphant larvae, several rods display an enlarged base (boxed areas), which TEM analysis revealed to consist of packets of outgrown disks extending well beyond the IS–OS interface and folding laterally. These outgrown disks are confined within the boundaries of the delimiting incisures (white arrowheads). The CPs are visible adjacent to the unaffected region but not adjacent to the basal enlargements of the OS (middle and right). Bars, 1 µm.