Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Jun 5;216(6):1579–1596. doi: 10.1083/jcb.201701165

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2017 Malinová et al.

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/).

PMC Copyright notice

Figure 7. — R2TP components are important for EFTUD2 stability and U5 snRNP maturation. (A) Levels of newly synthesized FFL-EFTUD2 after KD of R2TP and ZNHIT2. The graph displays FFL activity measured in extracts of HeLa cells transiently transfected with the indicated plasmid and siRNAs and then normalized first to RL activity (expressed from a cotransfected plasmid) and then to the ratio obtained with control siRNAs. Values are the means of at least three experiments, each done in triplicate. Error bars indicate SEM. (B) U5 snRNA accumulation in CBs after KD of RUVBL1/2. HeLa cells were treated with siRNAs against RUVBL1/2 or an NC siRNA. Green/left panels, U5 snRNA was detected by FISH; red/middle panels, coilin detected by IF; blue, DAPI. Bars, 10 µm.