Table 3.

Comparison of unweighted (RCT sample effect) and weighted (population effect) odds ratios of treatment effect on urine toxicology

Urine toxicology
	OR	95%CI		p	Comparison of the effect estimates from the unweighted and weighted models
CTN1
Unweighted	8.22	3.26	20.72	<.01
Weighted	8.26	1.43	47.76	.02	F(1, 225)=0.00, p=.99
CTN2
Unweighted	10.80	2.52	46.21	<.01
Weighted	59.76	10.89	327.87	<.01	F(1, 459)=2.24, p=.13
CTN3
Unweighted	1.84	1.28	2.64	<.01
Weighted	1.36	0.54	3.43	.52	F(1, 1031)=0.36, p=.55
CTN4
Unweighted	1.11	0.77	1.60	.59
Weighted	1.32	0.54	3.26	.54	F(1, 921)=0.13, p=.72
CTN5
Unweighted	1.18	0.80	1.72	.40
Weighted	1.79	0.80	3.99	.15	F(1, 845)=0.87, p=.35
CTN6
Unweighted	1.48	0.99	2.20	.05
Weighted	1.13	0.56	2.28	.74	F(1, 907)=0.44, p=.51
CTN7
Unweighted	0.87	0.51	1.49	.62
Weighted	0.48	0.13	1.82	.28	F(1, 771)=0.65, p=.42
CTN10
Unweighted	5.55	2.71	11.36	<.01
Weighted	4.71	0.29	76.54	.28	F(1, 307)=0.01, p=.91
CTN13
Unweighted	0.72	0.41	1.25	.24
Weighted	1.38	0.36	5.21	.64	F(1, 399)=0.78, p=.38
CTN30
Unweighted	0.72	0.41	1.25	.24
Weighted	1.38	0.36	5.21	.64	F(1, 1305)=0.00, p=.97