Impact of FPIES reactions on peripheral blood cells. Frequency of neutrophils (PMN), lymphocytes, monocytes, platelets, eosinophils, and basophils before (pre) and 4 to 6 hours after (post) food challenge. FPIES indicates subjects with reactions to foods, Outgrown indicates subjects who did not react to challenge. Bottom graphs summarize the change in circulating neutrophil and lymphocyte number (post-pre) in the 2 groups. *P < .05 and ****P < .0001.