Fig. 5.

Effects of allopurinol and quercetin on serum uric acid levels in hyperuricemic mice. The mice were orally administered with allopurinol or quercetin at the different doses indicated. The mice were then intraperitoneally injected with both IMP and GMP (400 mg each/kg body weight) to induce hyperuricemia. Normal control and model control groups were treated with vehicles instead of test samples and nucleotides, respectively. Each value represents mean ± SEM for eight to twelve mice (duplicate measurements per mouse) *significantly different from the model control groups at P < 0.05 (Dunnet test)