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. 2017 Jun 7;9:174. doi: 10.3389/fnagi.2017.00174

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Copyright © 2017 Tabei, Satoh, Ogawa, Tokita, Nakaguchi, Nakao, Kida and Tomimoto.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Changes in gray matter volume in different brain areas after intervention. The axis of ordinate displays changes based on β parameter estimates (with 90% confidence intervals) of the peak voxels within the respective clusters. As a region of interest (ROI), we compared pre- and post-intervention contrasts between the three groups to eliminate the possibility of pre-intervention differences in GMV: (post_ExM > pre ExM) > (post_Cont > pre_Cont) and (post_Ex > pre_Ex) > (post_ Cont > pre_Cont).