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. 2017 Jun 7;11:323. doi: 10.3389/fnins.2017.00323

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Copyright © 2017 Kosubek-Langer, Schulze and Scharff.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Newborn MSNs do not differ from mature MSNs in their DA receptor expression. (A) Dopamine receptors were highly expressed in the MSt and Area X shown here for D1A in a non-fluorescent in situ hybridization (blue precipitate). (B–D) New MSNs (BrdU+, arrow, fluorescent green label) expressed dopamine receptor D1A (dark precipitate). (E–G) New MSNs (BrdU+, arrow) expressed DA receptor D2. (H) There was no significant difference in the expression of dopamine receptor types between older neurons (BrdU-) and 42-day-old neurons (BrdU+). One data point represents one animal. Shown are mean and SD. Scale bars: 10 μm (B–F), 500 μm (A).