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. 2005 Jan 7;33(1):27–42. doi: 10.1093/nar/gki142

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© 2005, the authors Nucleic Acids Research, Vol. 33 No. 1 © Oxford University Press 2005; all rights reserved

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Inhibitory effects of oligonucleotides and conjugates in the HeLa cell reporter assay. (A and C) Firefly luciferase activity. (B and D): Control Renilla luciferase activity. A and B panels, left sections: free delivery of conjugate 4; centre sections: free delivery of conjugate 6; right sections: Lipofectamine 2000 delivery of conjugate 6. (C and D) Lipofectamine 2000 delivery from left to right: oligo B without linker, oligo B with 5′-thiol, oligo B with 5′-capped thiol, oligo C with 5′-thiol and oligo C with 5′-capped thiol.