Figure 5.
Confocal microscope images of the free uptake of fluorescein-labelled CPP conjugates containing additional cationic charge (green) into HeLa cells (nuclei stained red). Vertical Panels as in Figure 4 legend. Horizontally, (A) Conjugate 15 (OMe/LNA oligo B conjugated with R4-Tat), (B) Conjugate 17 (OMe/LNA oligo B conjugated with Tat-Tat), (C) Conjugate 18 (OMe/LNA oligo B conjugated with K4-Tat) and (D) Conjugate 18 (OMe/LNA oligo B conjugated with K4-Tat), 24 h experiment.