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(A) The four domains of neuronal SNARE protein: N Terminal Domian, Zero Ionic Layer, C Terminal Domain, Linker Domain; and involved four helices: snaptobrevin (blue), syntaxin (green), synaptosome-associated protein with relative molecular mass 25 K (SNAP25; magenta). (B) Top view of zero ionic layer. Reproduced with permission from Tekpinar and Zheng (2014).
