Figure 1.

Mifepristone blocks dexamethasone- but not alcohol-activation of gilz. MM6 cells were exposed to alcohol (0, 25, or 50 mM) or dexamethasone (Dex, 1 µM) for 24 h in the presence or absence of mifepristone (5 µM). GILZ expression from each treatment was measured by quantitative real-time PCR. Changes in GILZ expression were expressed by fold increases as compared to the base level of GILZ in the no treatment control. The data represent at least three independent experiments. The shown P-values by Student’s t-test indicate statistically significant differences. NS denotes non-significant difference.