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TAT-RasGAP317−326 can protect from E. coli peritonitis. (A–D) BALB/c mice (10 per group) were injected i.p. with 1.1 × 105 CFU E. coli O18 and 2 min (A,B) or 2 h later (C,D) with PBS, 1 mg/kg TAT-RasGAP317−326 or 4 mg/kg ceftriaxone. (A,C) Survival of mice. (B,D) Bacterial counts in the blood 24 h post-infection. The green dashed line indicates the limit of detection.
