Table 3.
Infant Neurodevelopmental Outcomes at 6 Months of Age
| Variable | Total – n (%) | Mbekweni – n (%) | TC Newman – n (%) | P-value |
|---|---|---|---|---|
| Number of infants; sets of twins | 112 | 57 (51); 1 | 55 (49); 0 | |
| Median age in months at study visit (IQR), corrected for prematurity at birth | 6.0 (5.7 to 6.2) | 6.0 (5.8 to 6.2) | 5.9 (5.7 to 6.3) | 0.397 |
| Cognitive scale | ||||
| Median score (IQR) | 10 (8 to 12) | 11 (8 to 12) | 10 (8 to 11) | 0.944 |
| Poor cognitive outcomes | 22 (20) | 13 (23) | 9 (16) | 0.391 |
| Communication scale | ||||
| Receptive communication, median score (IQR) | 11 (8 to 12) | 10 (9 to 12) | 11 (8 to 12) | 0.788 |
| Poor receptive communication outcomes | 25 (22) | 13 (23) | 12 (22) | 0.900 |
| Expressive communication, median score (IQR) | 11 (7 to 13.5) | 11 (9 to 14) | 10 (7 to 13) | 0.258 |
| Poor expressive communication outcomes | 29 (26) | 13 (23) | 16 (29) | 0.448 |
| Motor scale | ||||
| Fine motor, median score (IQR) | 13 (12 to 15) | 13 (12 to 15) | 13 (11 to 15) | 0.404 |
| Poor fine motor outcomes | 5 (4) | 2 (4) | 3 (5) | 0.676 |
| Gross motor, median score (IQR) | 11 (8 to 12) | 11 (9 to 12) | 11 (8 to 13) | 0.600 |
| Poor gross motor outcomes | 12 (11) | 4 (7) | 8 (15) | 0.234 |
| Social-emotional scale | ||||
| Median score (IQR) | 13 (11 to 15) | 13 (11 to 15) | 14 (11 to 16) | 0.218 |
| Poor social-emotional outcomes | 8 (7) | 1 (2) | 7 (13) | 0.030 |
| Adaptive behavior scale | ||||
| Communication, median score (IQR) | 11 (10 to 12) | 11 (9 to 12) | 11 (10 to 12) | 0.516 |
| Poor communication outcomes | 1 (0.9) | 0 (0) | 1 (2) | 0.491 |
| Health and safety, median score (IQR) | 10 (9 to 10) | 10 (9 to 10) | 10 (10 to 10) | 0.126 |
| Poor health and safety outcomes | 4 (4) | 3 (5) | 1 (2) | 0.618 |
| Leisure, median score (IQR) | 11 (9 to 12) | 10 (9 to 12) | 11 (10 to 13) | 0.056 |
| Poor leisure outcomes | 10 (9) | 4 (7) | 6 (11) | 0.524 |
| Self-care, median score (IQR) | 11 (10 to 12) | 10 (9 to 12) | 11 (10 to 12) | 0.256 |
| Poor self-care outcomes | 7 (6) | 4 (7) | 3 (5) | 1.000 |
| Self-direction, median score (IQR) | 10 (7 to 11) | 10 (7 to 11) | 10 (7 to 12) | 0.272 |
| Poor self-direction outcomes | 29 (26) | 15 (26) | 14 (25) | 0.917 |
| Social, median score (IQR) | 12 (11 to 13) | 11 (11 to 12) | 12 (11 to 13) | 0.016 |
| Poor social outcomes | 2 (2) | 2 (4) | 0 (0) | 0.496 |
| Motor, median score (IQR) | 11 (10 to 12) | 11 (10 to 12) | 11 (10 to 12) | 0.685 |
| Poor motor outcomes | 12 (11) | 5 (9) | 7 (13) | 0.554 |
| Any poor developmental outcome across all scales | 77 (69) | 40 (70) | 37 (67) | 0.740 |