Table 4.
Top 10 pathways having the largest gene count from enrichment analysis (p-value < 0.05)
| Pathway Name | Pathway Id |
Source Name |
Gene count | Genes in InnateDB for this entity |
p-value |
p-value (corrected) |
|---|---|---|---|---|---|---|
| Signaling by GPCR | 17449 | REACTOME | 30 | 1035 | 9.60E-04 | 4.54E-02 |
| GPCR ligand binding | 19266 | REACTOME | 20 | 433 | 1.95E-05 | 4.61E-03 |
| G alpha (q) signalling events | 13217 | REACTOME | 13 | 186 | 8.92E-06 | 4.22E-03 |
| Gastrin-CREB signalling pathway via PKC and MAPK | 13219 | REACTOME | 13 | 212 | 3.60E-05 | 5.67E-03 |
| G alpha (i) signalling events | 13220 | REACTOME | 13 | 231 | 8.71E-05 | 8.24E-03 |
| Neuroactive ligand-receptor interaction | 416 | KEGG | 13 | 275 | 4.84E-04 | 3.27E-02 |
| GPCR signaling | 16218 | INOH | 13 | 293 | 8.76E-04 | 4.60E-02 |
| Class A/1 (Rhodopsin-like receptors) | 13250 | REACTOME | 13 | 307 | 0.001341054 | 4.88E-02 |
| Transport of inorganic cations/anions and amino acids/oligopeptides | 13174 | REACTOME | 7 | 94 | 7.75E-04 | 4.58E-02 |
| LPA receptor mediated events | 15008 | PID NCI | 6 | 46 | 8.69E-05 | 1.03E-02 |