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. 2017 May 24;10(Suppl 1):30. doi: 10.1186/s12920-017-0269-y

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — An example result of significant epigenetic interactions between miRNA and methylation on NACC2 associated with survival outcome. a Patients were divided into 9 subgroups based on three quantiles of cg13979562 and hsa-miR-107. b Overall survival analysis was performed to show the relative survival in each of the L/L (N = 54) and H/H (N = 58) subgroups on NACC2. c Levels of gene expression of NACC2 between two subgroups (L/L vs. H/H) were significantly different (p = 4.69E-12)