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LGP-based tumor volume estimates covering time of treatment (Day 1 to Day 7) and follow up period (1 to 7 months). *M3 showed signs of hemorrhage at RS 2 (Day 4) and RS 3 (Day 7); bleeding zones were included in the field of treatment (GTV); see table 2. M4 experienced a tumor volume reduction of approximately 8% between RS 1 (day1) and RS 3 (day 7). M3 and M4 experienced significant tumor volume reduction at 1 month (89% and 90% respectively) and long lasting local control
