Table 3.
Designs of user-system interactions of the 20 selected pharmacogenomic CDSS
| System or project name | CDSS integration | Web-based access | Active or passive CDS | Included features |
|---|---|---|---|---|
| Clinical Pharmacogenomic Service (CPS) | yes | yes | active; passive | •pre-testing and post-testing alerts •reports •EHR data |
| Medicine Safety Code (MSC) | no | yes | passive | •reports •search engine •others (interface to upload genetic files; printed QR codes) |
| UW-PowerChart® prototype (s/n) | yes | no | active | •post-testing alerts •reports •EHR data |
| CU-case series study (s/n) | no | yes | passive | •reports |
| RIGHT (No.1) | yes | no | active | •pre-testing and post-testing alerts •EHR data •inbox messages |
| RIGHT (No. 2) | yes | no | active | •post-testing alerts •EHR data •inbox messages |
| RIGHT (No. 3) | yes | yes | active | •post-testing alerts •others (online portal for patients) |
| PREDICT | yes | yes | active; passive | •pre-testing and post-testing alerts •reports •EHR data •others (online portal for patients) |
| Personalized Medication Program (PMP) (No. 1) | yes | no | active; passive | •pre-testing and post-testing alerts •reports •EHR data •others (virtual PGx consult) |
| Personalized Medication Program (PMP) (No. 2) | yes | no | active | •post-testing alerts •inbox messages |
| PG4KDS | yes | no | active | •pre-testing and post-testing alerts •reports •EHR data •inbox messages |
| GeneSight | no | yes | passive | •reports |
| Genomic prescribing system (GPS) portal | no | yes | active; passive | •post-testing alerts •reports •search engine •others (virtual PGx consult) |
| CLIPMERGE PGx | yes | no | active | •post-testing alerts |
| Pharmacogenetics Testing Implementation Committee (PGTIC) (s/n) | yes | no | active | •pre-testing and post-testing alerts •EHR data •inbox messages |
| genAP | yes | no | passive | •reports |
| YouScript | no | no | passive | •reports |
| TreatGx | yes | no | passive | •EHR data •inbox messages |
| Coriell Personalized Medicine Collaborative (CPMC) (s/n) | no | yes | passive | •reports •inbox messages |
| Warfarin Dosing prototype (s/n) | yes | no | active | •post-test alerts |
Notes: “s/n” = surrogate name