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. 2005 Jan 13;33(1):356–365. doi: 10.1093/nar/gki189

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© 2005, the authors Nucleic Acids Research, Vol. 33 No. 1 © Oxford University Press 2005; all rights reserved

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Cell cycle analysis of different ES cell lines generated in this study. (A) Cell cycle profiles of ES cells fixed 7, 14 and 24 h after exposure to UV-C (1 J/m²). +/+, wild type; +/B, Rev1^+/; B/B, Rev1^B/B. The x-axis, DNA content; y-axis, number of cells as determined by propidium iodide staining. (B) Modelled frequencies of G1-, S- and G2/M phase cells in unexposed (left panels) and in UV-C-exposed (right panels) cell populations. It is noted that many late S phase cells, visible in panel A, are inadvertently categorized as G2/M cells by the software. Open circle, wild type; closed triangle, Rev1^B/B-254; open triangle, Rev1^L−/B; open square, Rev1^+/B; closed square, Rev1^L+/B.