Table 1.
Percentage frequencies of the most common copy number events in LGD, HGD and SCC samples
LGD | HGD | SCC | P value | |
---|---|---|---|---|
3p loss | 28.95 | 72.46 | 0.72 | 0.3994 |
4p loss | 13.16 | 44.93 | 0.33 | 0.9453 |
5q loss | 23.68 | 69.57 | 0.56 | 0.9787 |
9p loss | 26.32 | 65.22 | 0.50 | 0.7044 |
11 pq loss | 18.42 | 50.72 | 0.36 | 0.7893 |
18q loss | 7.89 | 42.03 | 0.50 | 0.0646 |
3q gain | 36.84 | 68.12 | 0.60 | 0.2041 |
5p gain | 39.47 | 62.32 | 0.51 | 0.0428 |
7 pq gain | 39.47 | 47.83 | 0.50 | 0.0067 |
8q gain | 50.00 | 57.97 | 0.59 | 0.0009 |
12p gain | 7.89 | 31.88 | 0.36 | 0.2404 |
Expected | 12 | 38 | 30 |
The p values that each event differs from the expected frequencies were calculated from the overall fraction of genome altered and total sample number for each group using a chi-squared test. As 11 regions were tested, p values below 0.0045 are considered significant