Table 2.
Clinical characteristics stratified according to OH in L (bioimpedance)
| OH | ||||
|---|---|---|---|---|
| Parameter | <−0.8 L, n=29 | −0.8 to +0.1 L, n=34 | >0.1 L, n=35 | P Value |
| Age, yr, median (range) | 63 (39–76) | 61 (25–78) | 69 (23–75) | 0.26 |
| Sex, men/women | 16/13 | 15/19 | 26/9 | 0.04 |
| Weight, kg, mean (95% CI) | 86 (81 to 92) | 82 (75 to 89) | 88 (82 to 93) | 0.34 |
| Height, cm, mean (95% CI) | 170 (166 to 175) | 170 (167 to 174) | 174 (172 to 176) | 0.15 |
| Body mass index, kg/m2, median (range) | 28 (24–41) | 28 (18–39) | 28 (20–39) | 0.30 |
| Office SBP, mmHg, mean (95% CI) | 133 (127 to 140) | 131 (126 to 135) | 135 (130 to 140) | 0.58 |
| Office DBP, mmHg, mean (95% CI) | 82 (78 to 86) | 80 (77 to 83) | 80 (76 to 83) | 0.60 |
| 24-h SBP, mmHg, mean (95% CI) | 124 (120 to 129) | 123 (120 to 127) | 129 (124 to 133) | 0.12 |
| 24-h DBP, mmHg, mean (95% CI) | 76 (72 to 79) | 76 (74 to 79) | 78 (75 to 81) | 0.51 |
| Hypertension, % | 90 | 94 | 91 | 0.81 |
| Treatment resistant hypertension, % | 10 | 15 | 17 | 0.74 |
| Number of BP medications, median (range) | 2 (0–4) | 3 (0–5) | 2 (0–6) | 0.24 |
| ACE inhibitor, % | 41 | 21 | 37 | 0.17 |
| ARB, % | 31 | 53 | 46 | 0.21 |
| β Blocker, % | 24 | 35 | 46 | 0.20 |
| Calcium channel antagonist, % | 21 | 44 | 49 | 0.05 |
| Diuretic, % | 45 | 50 | 49 | 0.92 |
| Aldosterone antagonist, % | 7 | 12 | 3 | 0.36 |
| Diabetes mellitus, % | 21 | 35 | 29 | 0.44 |
| Coronary artery disease, % | 10 | 3 | 11 | 0.38 |
| Cerebrovascular disease, % | 7 | 0 | 14 | 0.07 |
| Peripheral vascular disease, % | 0 | 6 | 3 | 0.40 |
| Diabetic nephropathy, % | 14 | 21 | 23 | 0.64 |
| Vascular nephropathy, % | 31 | 29 | 26 | 0.89 |
| Systemic disease, % | 10 | 21 | 17 | 0.54 |
| Primary glomerulopathy, % | 24 | 21 | 23 | 0.94 |
| Serum creatinine, mg/dl, median (range) | 1.4 (0.6–2.5) | 1.2 (0.8–2.0) | 1.3 (0.7–4.3) | 0.44 |
| eGFR, ml/min per 1.73 m2, median (range) | 53 (19–102) | 51 (27–100) | 49 (13–127) | 0.85 |
| UACR, mg/g creatinine, median (range) | 23 (1–1140) | 17 (2–1519) | 31 (2–1319) | 0.54 |
95% CI, 95% confidence interval; SBP, systolic blood pressure; DBP, diastolic blood pressure; ACE, angiotensin-converting enzyme; ARB, angiotensin receptor blockers; eGFR, estimated glomerular filtration rate; UACR, urinary albumin-to-creatinine ratio.