Table 3.
Serum biomarkers values according to CPR event or not (no time limit) and early CPR event after renal transplantation
| Event | CPR | Unpaired t Test | Early CPR | Unpaired | ||
|---|---|---|---|---|---|---|
| Positive | Negative | Positive | Negative | |||
| No. | 34 | 62 | 26 | 51 | ||
| Serum biomarkera | ||||||
| IgA, mg/ml | 3.19 (1.20) | 2.04 (1.43) | NS | 3.30 (1.32) | 2.94 (1.38) | NS |
| Norm Gd-IgA1, % | 35.5 (10.8) | 36.5 (13.5) | NS | 34.2 (9.6) | 36.0 (12.3) | NS |
| Total Gd-IgA1, U/ml | 110.6 (46.5) | 102.6 (58.2) | NS | 110.1 (49.3) | 101.3 (50.7) | NS |
| IgG, mg/ml | 10.93 (5.10) | 9.73 (4.17) | NS | 11.14 (5.57) | 9.75 (3.91) | NS |
| Norm IgG-autoAb, OD | 1.570 (0.430) | 1.400 (0.450) | <0.01; t=−1.80 | 1.600 (0.460) | 1.370 (0.380) | 0.02; t=−2.35 |
| Total IgG-autoAb, U/ml | 34.2 (17.7) | 28.5 (17.9) | NS (0.14) | 35.8 (19.5) | 27.5 (14.3) | 0.04; t=−2.12 |
| Norm IgA-autoAb, OD | 0.670 (0.630) | 0.580 (0.550) | NS | 0.740 (0.700) | 0.480 (0.270) | 0.02; t=−2.41 |
| Total IgA-autoAb, U/ml | 2.2 (2.2) | 1.9 (2.4) | NS | 2.5 (2.4) | 1.6 (1.6) | NS (0.06) |
Early CPR, CPR events occurring before 8.79 years after transplantation and corresponding to the 75th percentile of events with exclusion of eight recipients with later CPR and 11 recipients who died without previous recurrence; norm, normalized.
a
Laboratory data shown as mean (SD).