1. Description of populations.
| Trial | Country | Age (years) | On antiretroviral therapy (ART) | General population or subgroup | Mood disorders | |
| Inclusion criteria | Exclusion criteria | |||||
| Antoni 2006 | USA | 18 to 65 | Yes | Homosexual men | None stated | Current psychosis or panic disorder |
| Antoni 2008 | USA | 18 to 60 | Not stated | Women with evidence of CIN1 | None stated | Current major psychiatric illness |
| Berger 2008 | Switzerland | 18 to 65 | Yes | General population | None stated | Current major psychiatric disorder |
| Carrico 2005 | USA | Not stated | No (recruited largely during the era prior to highly active antiretroviral therapy (HAART; 1992 to 1997) |
Homosexual men | None stated | Current major psychiatric illness |
| Jones 2010 | USA | > 18 | Not stated | Minority women | None stated | Untreated major psychiatric illness |
| McCain 2003 | USA | > 18 | Yes | General population | None stated | Significant psychiatric illness |
| Safren 2012 | USA | 18 to 65 | Yes | Prior intravenous drug users | Current depressive mood disorder | Untreated or unstable major mental illness |
| Heckman 2007 | USA | Not stated | Not stated | Rural population | No inclusion or exclusion criteria related to psychological functioning were employed | No inclusion or exclusion criteria related to psychological functioning were employed |
| Heckman 2011 | USA | > 50 | Not stated | Individuals over the age of 50 | BDI‐II score is minimum 10 | Exclude severe depression or cognitive impairment |
| Sikkema 2013 | USA | Not stated | Not stated | History of child sexual abuse | Not stated | Not stated |
| Peltzer 2012 | South Africa | > 18 | Yes | Individuals with ART adherence problem/new antiretroviral (ARV) medication users (6 to 24 months of ARV use) | Not stated | Not stated |
| Chesney 2003 | USA | 21 to 60 | No | Homosexual men | Reported depressed mood 10 or higher on CES‐D scale | Major depressive disorder or other psychotic disorders |
| Bormann 2006 | USA | 18 to 65 | Not stated | Adult men and women (50% homosexual) | Not stated | Cognitive impairment of active psychosis |
| Duncan 2012 | USA | Not specified | Yes | Adult men and women who reported distress associated with side effects from ART treatment | Reporting a level of side effect‐related bother for the previous 30 days at or above eight (corresponding to the 40th percentile in another sample) on the side effect and symptom distress scale | Severe cognitive impairment, active psychosis, or active substance abuse |
| Gayner 2012 | Canada | Not specified | Not stated | Homosexual men | None stated | Active current major depression, substance abuse, or significant cognitive deficit |
| Nakimuli‐Mpungu 2015 | Uganda | > 19 | Not stated | Both men and women | People with major depression on Mini Psychiatric Interview Scale | The trial excluded individuals with a severe medical disorder such as pneumonia or active tuberculosis, psychotic symptoms, and hearing or visual impairment. |
Abbreviations: ART: antiretroviral therapy; ARV: antiretroviral.