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. 2017 Mar 14;2017(3):CD010806. doi: 10.1002/14651858.CD010806.pub2

Comparison 1. Group therapy (CBT) versus control.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1 Depression scores 10   Std. Mean Difference (IV, Random, 95% CI) Subtotals only
1.1 Baseline mean scores 10 1600 Std. Mean Difference (IV, Random, 95% CI) 0.05 [‐0.05, 0.15]
1.2 Mean score at end of group sessions (10 to 12 weeks after randomization) 9 1142 Std. Mean Difference (IV, Random, 95% CI) ‐0.17 [‐0.29, ‐0.05]
1.3 Mean score at longest follow‐up (6 to 15 months after randomization) 10 1139 Std. Mean Difference (IV, Random, 95% CI) ‐0.26 [‐0.42, ‐0.10]
2 Depression scores at longest follow‐up; subgrouped by depression score used 10   Mean Difference (IV, Random, 95% CI) Subtotals only
2.1 Beck depression inventory (score out of 63) 6 753 Mean Difference (IV, Random, 95% CI) ‐1.41 [‐2.61, ‐0.21]
2.2 Hospital Anxiety and Depression score (score out of 21) 1 71 Mean Difference (IV, Random, 95% CI) ‐2.12 [‐3.90, ‐0.34]
2.3 Geriatric depression score (score out of 30) 1 160 Mean Difference (IV, Random, 95% CI) ‐1.48 [‐2.83, ‐0.13]
2.4 Centre for Epidemiological Studies (score out of 60) 1 70 Mean Difference (IV, Random, 95% CI) 0.30 [‐4.03, 4.63]
2.5 Self‐reported questionnaire (score out of 20) 1 85 Mean Difference (IV, Random, 95% CI) ‐2.5 [‐3.91, ‐1.09]
2.6 Profile of mood states (depression) (score out of 60) 1 101 Mean Difference (IV, Random, 95% CI) ‐4.30 [‐10.47, 1.87]
2.7 Montgomery‐Asberg Depression Rating Scale (score out of 60) 1 66 Mean Difference (IV, Random, 95% CI) ‐4.72 [‐9.67, 0.23]
3 Depression scores (trials with mean scores in the range of depression at baseline) 5   Std. Mean Difference (IV, Random, 95% CI) Subtotals only
3.1 Baseline mean scores 5 790 Std. Mean Difference (IV, Random, 95% CI) 0.04 [‐0.10, 0.18]
3.2 Mean score at longest follow‐up 5 628 Std. Mean Difference (IV, Random, 95% CI) ‐0.20 [‐0.46, 0.06]
4 Depression scores at longest follow‐up; subgrouped by control 10   Std. Mean Difference (IV, Random, 95% CI) Subtotals only
4.1 Standard care ± a minimal intervention (< 1 day) 6 595 Std. Mean Difference (IV, Random, 95% CI) ‐0.24 [‐0.45, ‐0.04]
4.2 Alternative group sessions 3 300 Std. Mean Difference (IV, Random, 95% CI) ‐0.25 [‐0.71, 0.22]
4.3 Individual therapy 2 389 Std. Mean Difference (IV, Random, 95% CI) ‐0.22 [‐0.42, ‐0.01]
5 Depression scores (trials with mean scores in the normal range at baseline) 5   Std. Mean Difference (IV, Random, 95% CI) Subtotals only
5.1 Baseline mean scores 5 810 Std. Mean Difference (IV, Random, 95% CI) 0.10 [‐0.11, 0.30]
5.2 Mean score at longest follow‐up (6 to 15 months after randomization) 5 511 Std. Mean Difference (IV, Random, 95% CI) ‐0.30 [‐0.48, ‐0.13]
6 Depression scores at longest follow‐up; subgrouped by primary focus of intervention 10   Std. Mean Difference (IV, Random, 95% CI) Subtotals only
6.1 Stress management 3 216 Std. Mean Difference (IV, Random, 95% CI) ‐0.46 [‐0.73, ‐0.18]
6.2 Coping 3 396 Std. Mean Difference (IV, Random, 95% CI) ‐0.14 [‐0.37, 0.08]
6.3 Self‐efficacy 1 229 Std. Mean Difference (IV, Random, 95% CI) ‐0.13 [‐0.39, 0.13]
6.4 Depression 1 85 Std. Mean Difference (IV, Random, 95% CI) ‐0.75 [‐1.19, ‐0.30]
6.5 Adherence and depression 1 66 Std. Mean Difference (IV, Random, 95% CI) ‐0.43 [‐0.92, 0.06]
6.6 Adherence 1 147 Std. Mean Difference (IV, Random, 95% CI) 0.03 [‐0.30, 0.35]
7 Depression scores at longest follow‐up; subgrouped by gender 10 1139 Std. Mean Difference (IV, Random, 95% CI) ‐0.26 [‐0.42, ‐0.10]
7.1 Men only 3 215 Std. Mean Difference (IV, Random, 95% CI) ‐0.26 [‐0.55, 0.04]
7.2 Women only 1 229 Std. Mean Difference (IV, Random, 95% CI) ‐0.13 [‐0.39, 0.13]
7.3 Both men and women 6 695 Std. Mean Difference (IV, Random, 95% CI) ‐0.31 [‐0.55, ‐0.07]
8 Anxiety scores 4   Std. Mean Difference (IV, Random, 95% CI) Subtotals only
8.1 Baseline mean scores 4 697 Std. Mean Difference (IV, Random, 95% CI) 0.11 [‐0.05, 0.27]
8.2 Mean score at end of group sessions (10 to 12 weeks after randomization) 3 420 Std. Mean Difference (IV, Random, 95% CI) ‐0.01 [‐0.25, 0.22]
8.3 Mean score at longest follow‐up (12 to 15 months after randomization) 4 471 Std. Mean Difference (IV, Random, 95% CI) ‐0.12 [‐0.31, 0.06]
9 Anxiety scores: at longest follow‐up; subgrouped by anxiety scale used 4   Mean Difference (IV, Random, 95% CI) Subtotals only
9.1 State trait anxiety inventory (score between 20 and 80) 1 70 Mean Difference (IV, Random, 95% CI) ‐0.80 [‐6.06, 4.46]
9.2 Modified State Trait Anxiety Inventory (score between 10 and 40) 1 229 Mean Difference (IV, Random, 95% CI) ‐0.61 [‐2.09, 0.87]
9.3 Hospital Anxety and Depression Scale (score out of 21) 1 71 Mean Difference (IV, Random, 95% CI) ‐2.4 [‐4.92, 0.12]
9.4 Profile of Mood States (score out of 36) 1 101 Mean Difference (IV, Random, 95% CI) 0.20 [‐2.64, 3.04]
10 Anxiety scores: at longest follow‐up; subgrouped by control 4   Mean Difference (IV, Random, 95% CI) Subtotals only
10.1 Standard care ± a minimal intervention (< 1 day) 2 172 Mean Difference (IV, Random, 95% CI) ‐1.18 [‐3.73, 1.36]
10.2 Alternative group therapy 1 70 Mean Difference (IV, Random, 95% CI) ‐0.80 [‐6.06, 4.46]
10.3 Individual therapy 1 229 Mean Difference (IV, Random, 95% CI) ‐0.61 [‐2.09, 0.87]
11 Stress scores 5   Std. Mean Difference (IV, Random, 95% CI) Subtotals only
11.1 Baseline mean scores 5 695 Std. Mean Difference (IV, Random, 95% CI) 0.12 [‐0.03, 0.27]
11.2 Mean score at end of group sessions 4 533 Std. Mean Difference (IV, Random, 95% CI) ‐0.06 [‐0.23, 0.12]
11.3 Mean score at longest follow‐up 5 507 Std. Mean Difference (IV, Random, 95% CI) ‐0.04 [‐0.23, 0.15]
12 Stress scores at longest follow‐up; subgrouped by stress score used 5   Mean Difference (IV, Random, 95% CI) Subtotals only
12.1 Perceived stress score (score out of 40) 1 70 Mean Difference (IV, Random, 95% CI) ‐0.70 [‐3.77, 2.37]
12.2 Dealing with illness scale 1 69 Mean Difference (IV, Random, 95% CI) ‐1.80 [‐7.62, 4.02]
12.3 HIV‐related life‐stressor burden score (score out of 5) 1 166 Mean Difference (IV, Random, 95% CI) 0.08 [‐0.06, 0.22]
12.4 Life experiences survey (score out of 3) 1 39 Mean Difference (IV, Random, 95% CI) ‐1.36 [‐3.00, 0.28]
12.5 Impact of event scale (score out of 75) 2 232 Mean Difference (IV, Random, 95% CI) ‐1.33 [‐3.60, 0.95]
13 Stress scores at longest follow‐up; subgrouped by control 5   Mean Difference (IV, Random, 95% CI) Subtotals only
13.1 Standard care ± a minimal intervention (< 1 day) 3 274 Mean Difference (IV, Random, 95% CI) ‐0.37 [‐1.46, 0.71]
13.2 Alternative group therapy 4 454 Mean Difference (IV, Random, 95% CI) 0.09 [‐0.05, 0.22]
13.3 Individual therapy 0 0 Mean Difference (IV, Random, 95% CI) 0.0 [0.0, 0.0]
14 Coping scores 5   Std. Mean Difference (IV, Random, 95% CI) Subtotals only
14.1 Baseline mean scores 5 1022 Std. Mean Difference (IV, Random, 95% CI) 0.01 [‐0.11, 0.14]
14.2 Mean score at end of group sessions 5 762 Std. Mean Difference (IV, Random, 95% CI) 0.02 [‐0.16, 0.19]
14.3 Mean score at longest follow‐up (6 months after randomization) 5 697 Std. Mean Difference (IV, Random, 95% CI) 0.04 [‐0.11, 0.19]
15 Coping scores at longest follow‐up; subgrouped by coping score used 5   Mean Difference (IV, Random, 95% CI) Subtotals only
15.1 Dealing with illness: coping subscale (score out of 120) 1 69 Mean Difference (IV, Random, 95% CI) 1.90 [‐1.79, 5.59]
15.2 Cognitive behavioural self‐efficacy scale (score out of 28) 1 229 Mean Difference (IV, Random, 95% CI) ‐0.16 [‐1.29, 0.97]
15.3 Coping self‐efficacy scale (score out of 260) 2 236 Mean Difference (IV, Random, 95% CI) 1.76 [‐6.53, 10.05]
15.4 Avoidant coping scale (score out of 69) 1 163 Mean Difference (IV, Random, 95% CI) ‐1.70 [‐5.26, 1.86]
16 Coping scores at longest follow‐up; subgrouped by control 5   Mean Difference (IV, Random, 95% CI) Subtotals only
16.1 Standard care ± a minimal intervention (< 1 day) 2 235 Mean Difference (IV, Random, 95% CI) 0.19 [‐0.21, 0.59]
16.2 Alternative group therapy 4 454 Mean Difference (IV, Random, 95% CI) ‐0.25 [‐0.67, 0.17]
16.3 Individual therapy 1 229 Mean Difference (IV, Random, 95% CI) ‐0.16 [‐1.29, 0.97]