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. Author manuscript; available in PMC: 2018 Apr 1.
Published in final edited form as: Int Rev Psychiatry. 2017 Feb 10;29(2):191–204. doi: 10.1080/09540261.2017.1282438

Table 1.

Summary of the hardware platforms currently available that could support closed-loop DBS

Platforms Advantages Disadvantages
Activa PC+S

  • Recording and stimulation on the same lead

  • System optimized for stimulation

  • Suitable for DBS-like use with much longer and frequent stimulation

  • Easily supports existing clinically effective approaches

  • Battery powered

  • The recording and stimulating systems are partitioned

  • Rapid battery depletion with frequent recording
Responsive Neurostimulation System (RNS)

  • Built-in signal processing algorithms

  • System configured by default for closed-loop control

  • System optimized for recording

  • Suitable for short and intermittent stimulation such as seizure-preventive stimulation, control of brief symptoms

  • Battery powered

  • Cannot record and stimulate at the same lead

  • Rapid battery depletion with frequent stimulation