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. Author manuscript; available in PMC: 2017 Jun 7.
Published in final edited form as: Stroke. 2016 Dec 27;48(2):379–387. doi: 10.1161/STROKEAHA.116.014735

Table 2.

Lifetime Cost-Effectiveness Results for Base Case and Sensitivity Analyses

SST+tPA
Costs ($)
tPA Costs
($)
Δ Costs ($) (95% CI) SST+tPA
QALYs
tPA
QALYs
Δ QALYs (95% CI)* ICER ($ per QALY) %
Dominant
%
Dominated
%
<$50K
Base case 215 781 238 984 −23 203 (−56 946 to 12 933) 6.789 5.046 1.743 (0.760–2.786) Dominant 90.0 0.0 100
Benefit in life-years 215 781 238 984 −23 203 (−56 946 to 12 933) 9.128 7.920 1.208* (0.287–2.168) Dominant 89.5 0.1 99.9
Sensitivity analyses
 Historical costs 135 876 127 368 8507 (−6565 to 23 804) 6.789 5.046 1.743 (0.760–2.786) 4881 13.8 0.0 99.9
 No nursing home costs 152 861 129 371 23 490 (12 960 to 34 573) 6.789 5.046 1.743 (0.760–2.786) 12 631 0.0 0.0 99.9
 No long-term costs 57 030 44 752 12 278 (5786 to 19 080) 6.789 5.046 1.743 (0.760–2.786) 7044 0.0 0.0 99.8
 Benefit in DALYs 215 781 238 984 −23 203 (−56 946 to 12 933) 7.235 5.156 2.079 (0.933–3.253) Dominant 90.0 0.0 100
 Calibration factor 1 259 157 298 738 −39 581 (−84 455 to 8897) 8.396 6.306 2.089 (0.904–3.341) Dominant 95.0 0.0 100
 Calibration factor 3 180 912 192 682 −11 770 (−38 382 to 16 280) 5.448 4.013 1.436 (0.622–2.273) Dominant 80.6 0.0 100
 Calibration factor 5 149 596 152 580 −2 984 (−23 325 to 18 445) 4.200 3.066 1.134 (0.486–1.781) Dominant 60.4 0.0 99.8

CI indicates confidence interval; DALY, disability-adjusted life-years; ICER, incremental cost-effectiveness ratio; QALY, quality-adjusted life-years; SST, Solitaire stent thrombectomy; and tPA, tissue-type plasminogen activator.

*

Results in QALYs unless otherwise specified as life-years or DALYs.