Table 3.
Multivariate analysis of factors related to survival among nonsmokers
| Variable | Level | Hazard Ratio | 95% CI | P Value |
|---|---|---|---|---|
| Age, yr | 51–59 | 1.00 | Reference | |
| 60–70 | 1.05 | 0.60–1.86 | 0.86 | |
| 70–79 | 1.06 | 0.60–1.85 | 0.85 | |
| 80+ | 1.08 | 0.56–2.08 | 0.81 | |
| Sex | Male | 1.00 | Reference | |
| Female | 0.76 | 0.52–1.13 | 0.18 | |
| Race/ethnicity | Non-Hispanic white | 1.00 | Reference | |
| Hispanic or Latino | 2.06 | 1.07–3.99 | 0.03 | |
| African American | 1.75 | 0.96–3.18 | 0.07 | |
| Asian/Pacific Islander | 0.83 | 0.47–1.49 | 0.53 | |
| Multiple/other/unknown | 0.80 | 0.30–2.16 | 0.66 | |
| Comorbidity | None | 1.00 | Reference | |
| Mild | 1.49 | 0.87–2.55 | 0.15 | |
| Moderate | 1.67 | 0.92–3.01 | 0.09 | |
| Severe | 3.21 | 1.52–6.79 | 0.002 | |
| Insurance | Private/HMO | 1.00 | Reference | |
| Medicare | 1.06 | 0.60–1.88 | 0.84 | |
| Medicaid/other public | 1.56 | 0.67–3.63 | 0.30 | |
| Unknown/none | 1.28 | 0.52–3.18 | 0.59 | |
| Income | <$20,000 | 1.00 | Reference | |
| $20,000–$40,000 | 0.82 | 0.45–1.46 | 0.49 | |
| $40,000–$60,000 | 0.71 | 0.32–1.57 | 0.39 | |
| $60,000 or more | 0.56 | 0.26–1.20 | 0.14 | |
| Education | Some grade school | 1.00 | Reference | |
| High school graduate | 1.22 | 0.65–2.29 | 0.54 | |
| Some college or more | 2.00 | 1.02–3.93 | 0.04 | |
| Health care setting | Nonintegrated | 1.00 | Reference | |
| Integrated | 0.79 | 0.53–1.19 | 0.26 | |
| VHA | 0.72 | 0.27–1.90 | 0.50 | |
| Histology | Adenocarcinoma | 1.00 | Reference | |
| Squamous cell | 1.35 | 0.73–2.51 | 0.33 | |
| Small cell | 1.80 | 0.58–5.56 | 0.31 | |
| Large cell | 2.33 | 0.90–6.07 | 0.08 | |
| Undifferentiated/other | 1.73 | 1.12–2.68 | 0.01 | |
| Stage | Local | 1.00 | Reference | |
| Regional/distant | 3.92 | 2.08–7.37 | <0.0001 | |
| Surgery | Yes | 1.00 | Reference | |
| No | 5.25 | 3.00–9.21 | <0.0001 | |
| Chemotherapy | Yes | 1.00 | Reference | |
| No | 2.39 | 1.50–3.81 | 0.0003 | |
| Radiotherapy | Yes | 1.00 | Reference | |
| No | 1.48 | 0.98–2.23 | 0.06 |
Definition of abbreviations: CI = confidence interval; HMO = health maintenance organization; VHA = Veterans Health Administration.