Table 3.
Factor | Severe scoliosis | Hazard ratio (95% CI), p-value | |
---|---|---|---|
N(%) or Mean ±SD | |||
Scoliosis at baseline | None | 27 (5) | 1 |
1 to <20° Cobb angle | 47 (26) | 6.68 (3.97, 11,23), p<0.0001 | |
20 to <40° Cobb angle | 39 (41) | 20.3 (11.3, 36.5), p<0.0001 | |
Mutation | Mild | 21 (10) | 1 |
Moderate | 34 (14) | 1.31 (0.76, 2.27), p=0.34 | |
Severe | 54 (19) | 1.84 (1.10, 3.08), p=0.021 | |
Age at baseline | 8±4 | 0.73 (0.66, 0.81), p<0.0001 |