Figure 2.
Overexpression of Notch enhanced cell migration and invasion. (A) Cell detachment and attachment were measured in PC-3 ICN cells. *P<0.05 vs PC-3 cells. (B) Wound healing assay was applied for detection of cell migration in PC-3 cells with ICN transfection. (C) Left panel: Matrigel migration and invasion chamber assays were performed to examine the invasive activity of PC-3 cells transfected with ICN. Right panel: quantitative results are illustrated for left panel. *P<0.05 vs PC-3 cells.