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. 2017 Apr 7;16(10):999–1007. doi: 10.1080/15384101.2017.1312237

Figure 3.

Figure 3.

Down-regulation of Notch-1 retarded cell migration and invasion. (A) Western blotting was conducted to measure the efficacy of Notch-1 siRNA for knocking down Notch-1 in PC-3 cells. CS: control siRNA; NS: Notch-1 siRNA. (B) Cell detachment and attachment were measured in PC-3 cells transfected with Notch-1 siRNA. *P<0.05 vs PC-3 cells. (C) Left panel: Matrigel migration and invasion chamber assays were conducted to detect the invasive activity of PC-3 cells transfected with Notch-1 siRNA. Right panel: quantitative results are illustrated for left panel. *P<0.05 vs control.