Table 3.
Characteristics of patients infected with rhinovirus A (RV-A) compared with patients infected with rhinovirus C (RV-C).
| RV-A (n = 23) |
RV-C (n = 10) |
p-value | |
|---|---|---|---|
| Gender (% females) | 74 | 60 | 0.42 |
| Age | 28 (9) | 30 (9) | 0.83 |
| Smokers (% never; former; current) | 65; 22; 13 | 80; 0; 20 | 0.27 |
| Packyears (among former and current smokers) | 7 (0.1–17) | 1 (0.1–6) | 0.29 |
| Atopic (%) | 65 | 60 | 0.78 |
| ICS dose (daily budesonide eq.) | 400 (0–1600) | 0 (0–2400) | 0.83 |
| FEV1%pred. | 77.7 (15.9) | 76.2 (17.7) | 0.81 |
| FVC %pred. | 86.0 (15.0) | 87.4 (12.3) | 0.80 |
| FeNO (ppb)a | 26 (19–36) | 38 (25–56) | 0.18 |
| ACQ | 3.5 (1.3) | 3.4 (1.5) | 0.98 |
| Blood eosinophils (× 109 cells/L) | 0.06 (0–0.52) | 0.18 (0.02–1.32) | 0.04 |
| Blood neutrophils (× 109 cells/L) | 6.3 (2.1–14.1) | 6.3 (2.8–11.2) | 0.95 |
| Total IgE (× 103 IU/L)a | 214 (98–470) | 142 (35–574) | 0.70 |
| CRP (mg/L)a |
9.1 (6.2–13.4) |
7.8 (3.3–18.8) |
0.56 |
| n = 16 |
n = 10 |
||
| Sputum total cell count (× 106/ml)a | 0.8 (0.4–1.5) | 1.9 (1.0–3.6) | 0.06 |
| Sputum eosinophils (× 106/ml)a | 0.04 (0.02–0.10) | 0.19 (0.09–0.40) | 0.01 |
| Sputum %-eosinophilsa | 1.1 (0.3–3.4) | 1.6 (0.2–11.4) | 0.66 |
| Sputum neutrophils (× 106/ml)a | 0.3 (0.1–0.8) | 1.0 (0.3–3.1) | 0.12 |
| Sputum %-neutrophilsa | 42.4 (24.7–72.9) | 52.5 (29.1–94.4) | 0.58 |
a
Log-transformed and presented as geometric mean (95% CI).