Table 1.
The genes of the (+)-training set (without orthologs). Marked with asterisks are those included in the "seed" set.
No | Gene name | Accessin no. And LocusLinkID | Experimental evidence | Additional information | Participation in anti-Pseudomonas response |
1 | Monocyte chemoattractant protein-1, MCP-1* | EMBL: D26087 | Microarray [66], other experiments [20,21,38] | Is well know as expressed in antibacterial response | 100% |
2 | β-defensin* | LocusLinkID: 1673 | [15,18,19,39,40] | Is well known as expressed in antibacterial response; important target gene in innate immunity | 100% |
3 | Interferon regulatory factor 1, IRF-1* | LocusLinkID: 3659 | Microarray [66] | Known to be expressed in epithelial cells | probable |
4 | Equilibrate nucleoside transporter 1, SLC29a1 | LocusLinkID: 2030 | Microarray [66] | ||
5 | Proteinkinase C η type, PKCη* | LocusLinkID: 5583 | Microarray [66] TRANSPATH® | Important link in Ca2+-connected pathways | probable |
6 | Folypolyglutamate synthase, FPGS | Ensembl : ENSG00000136877 | Microarray [66] | ||
7 | RhoB* | LocusLinkID: 388 | Microarray [66] | is induced as part of the immediate early response in different systems | probable |
8 | Origin recognition complex subunit 2, hORC2L | LocusLinkID: 4999 | Microarray [66] | ||
9 | Transcription factor TEL2* | LocusLinkID: 51513 | Microarray [66] | Transcription factor | probable |
10 | Interleukin 8, IL8* | EPD: EP73083LocusLinkID: 3576 | [10,11,26,44,45] | Is well know as expressed in antibacterial response | 100% |
11 | Transcription factor ELF3* | LocusLinkID: 1999 | Microarray [66] | Transcription factor | probable |
12 | Mucin 1(mouse gene), MUC1* | RefSeq: NM_013605 | [17,27,28,36,47] | Different mucins are shown as expressed in antibacterial response | 100% |
13 | NF-kappaB inhibitor alpha, IkBa* | LocusLinkID: 4792 EPD: EP73215 | Microarray [66] | NF-kB inhibitor, the main link in NF-kB-targeting pathways | Very high |
14 | Tissue Factor Pathway Inhibitor 2, TFPI | LocusLinkID: 7980 EPD: EP73430 | Microarray [66] | ||
15 | Urokinase-type plasminogen activator precursor, PLAU | LocusLinkID: 5328 | Microarray [66] | ||
16 | c-jun* | Microarray [66] | Transcription factor | probable | |
17 | Cytochrom P450 dioxin-inducible* | LocusLinkID: 1545 | Microarray [66] | Stress-inducible | probable |
18 | Dyphtheria toxin resistance protein, DPH2L2 | EPD: EP74285 | Microarray [66] |