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. 2017 Jun 7;12(6):e0178541. doi: 10.1371/journal.pone.0178541

Fig 6. Host renal cell production of cytokines and cytotoxicity in response to ESBL isolate 7.

Fig 6

A) IL-6 and IL-8 production from A498 renal epithelial cells after stimulation for 6 h with the original ESBL7 isolate or with ESBL7 that have been pre-exposed 20 times to CORM-2 (250 μM) or vehicle (2.5% DMSO). B) Host renal cell cytotoxicity measured as LDH-release during the same conditions as in panel A and normalized to unstimulated and lysed control cells. Data are presented as mean ± SEM from three independent experiments. Asterisk denotes statistical significance (*p<0.05).