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. 2017 Jun 7;12(6):e0179132. doi: 10.1371/journal.pone.0179132

Table 3. Multiple linear regression analyses for orthostatic intolerance symptom scores.

Variables B 95% CI p-value R2
Model 1 0.234
 Age, yr 0.045 -0.037–0.127 0.28
 Sex, female 2.127 -0.311–4.566 0.086
 Body mass index, kg/m2 -0.232 -0.605–0.142 0.221
 Current smoking 4.687 0.821–8.554 0.018
 Serum BUN, mg/dL -0.340 -0.687–0.007 0.054
 Serum Sodium, mmol/L -0.485 -1.082–0.113 0.11
 Mean total DBP, mmHg -0.006 -0.188–0.177 0.952
 Total DBPVCV, % 0.460 0.042–0.877 0.031
 Constant 81.601 -3.557–166.76 0.06
Model 2 0.24
 Age, yr 0.43 -0.038–0.124 0.29
 Sex, female 2.099 -0.324–4.522 0.089
 Body mass index, kg/m2 -0.235 -0.597–0.126 0.199
 Current smoking 4.384 0.537–8.231 0.026
 Serum BUN, mg/dL 0.324 -0.67–0.022 0.066
 Serum Sodium, mmol/L -0.522 -1.116–0.072 0.084
 Mean awake DBP, mmHg -0.016 -0.189–0.158 0.857
 Awake DBPVCV, % 0.429 0.07–0.787 0.02
 Constant 87.715 2.892–172.54 0.043

The total score of orthostatic intolerance questionnaires is a dependent variable (n = 103). B denotes the unstandardized coefficient. Model 1, F(8, 94) = 3.589, p = 0.001, blood pressure and variability variables derived from the total recordings; Model 2, F(8, 94) = 3.719, p = 0.001, blood pressure and variability variables derived from the awake recordings. Abbreviations: CI, confidence interval; BUN, blood urea nitrogen; DBP, diastolic blood pressure; DBPVCV, diastolic blood pressure variability measured by the coefficient of variation.