Table 1. List of the miRNA expression datasets used in this study.

No.	miRNA expression datasets of	source
1	Young and replicative senescent human umbilical vein endothelial cells	GEO: GSE37092
2	Young and oncogenic H-Ras V12-induced senescent (RIS) IMR90 cells	http://www.cuilab.cn
3	Young (developmental) and aging macaque brain	GEO: GSE18013
4	Human aging adipose	GEO: GSE64566
5	The umbilical vein endothelial cells	GEO: GSE37092