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. Author manuscript; available in PMC: 2017 Jun 7.
Published in final edited form as: Small. 2016 Aug 29;12(40):5612–5621. doi: 10.1002/smll.201601829

Figure 2.

Figure 2

Automated staining device to enhance the speed and reproducibility of the REMI staining procedure, in which a multiplexed panel of SERS NPs is topically applied on the surfaces of fresh tissues. a) The staining device is equipped with a suction plate (b) to secure the tissue from above without interfering with the staining of the bottom surface of the tissue. The device incorporates a servo motor to dip the tissue into and out of a NP mixture (d,e), along with high-frequency vibration from two vibration motors (c) to further enhance the tissue staining. The fully assembled device (f) contains three adjustable suction plates to secure and stain multiple tissue specimens of varying thickness.